We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Top 10 developments in lupus nephritis.
- Authors
Chen, Teresa K; Fine, Derek M
- Abstract
Lupus nephritis affects up to 60 % of patients with systemic lupus erythematosus and is associated with worse clinical outcomes. Traditionally, it has been treated with high-dose immunosuppression consisting of cyclophosphamide and prednisone; however, recent trials have demonstrated mycophenolate mofetil as a safe and effective alternative for both induction and maintenance of disease. Other progress has been made in our understanding of the pathogenesis of lupus nephritis, outcomes in renal transplantation, and associations with genetic risk factors. This review highlights key developments in our understanding of lupus nephritis over the past decade.
- Publication
Current rheumatology reports, 2013, Vol 15, Issue 9, p358
- ISSN
1534-6307
- Publication type
Journal Article
- DOI
10.1007/s11926-013-0358-7