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- Title
Progress in the treatment of neuroendocrine tumors.
- Authors
Chan, Jennifer A; Kulke, Matthew H
- Abstract
Traditional treatments for patients with advanced neuroendocrine tumors include surgical debulking, hepatic embolization, somatostatin analogues, and interferon-alpha. Patients with pancreatic neuroendocrine tumors also may benefit from treatment with the alkylating agents streptozocin or temozolomide. In recent years, several promising new approaches have been investigated in patients with advanced neuroendocrine tumors. One such approach has been the use of radiopeptide therapy targeting somatostatin receptors. Additionally, agents targeting the vascular endothelial growth factor pathway and mammalian target of rapamycin have shown preliminary evidence of activity and are currently being evaluated in large randomized studies.
- Publication
Current oncology reports, 2009, Vol 11, Issue 3, p193
- ISSN
1534-6269
- Publication type
Journal Article
- DOI
10.1007/s11912-009-0028-0