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Title
Inclusion body myositis: review of recent literature.
Authors
Greenberg, Steven A
Abstract
Inclusion body myositis (IBM) is a progressive inflammatory skeletal muscle disease of unknown cause and without effective treatment. This article discusses existing literature, emphasizing disease mechanisms and models. In particular, it addresses limitations in the beta-amyloid-mediated theory of IBM myofiber injury, flawed rationales of animal models of this disease, and recent reports regarding treatment.
Publication
Current neurology and neuroscience reports, 2009, Vol 9, Issue 1, p83