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- Title
Is this bone infected or not? Differentiating neuro-osteoarthropathy from osteomyelitis in the diabetic foot.
- Authors
Berendt, Anthony R; Lipsky, Benjamin
- Abstract
Osteomyelitis (bone infection) and neuro-osteoarthropathy (Charcot arthropathy) are limb-threatening complications of diabetic neuropathy with very different therapies. Distinguishing between them may be difficult, but it is important. In Charcot arthropathy, noninfectious soft tissue inflammation accompanies rapidly progressive destruction, first of joints, then of bone. This occurs in a well-vascularized and severely neuropathic, but nonulcerated, foot. In osteomyelitis, chronic soft tissue ulceration precedes infection of bone, which may be physically exposed. Magnetic resonance imaging and bone biopsy are the preferred diagnostic tests, provided adequate technical and interpretive skills are available.
- Publication
Current diabetes reports, 2004, Vol 4, Issue 6, p424
- ISSN
1534-4827
- Publication type
Journal Article
- DOI
10.1007/s11892-004-0051-3