Works matching DE "CELLULAR signal transduction"

Results: 5000

AUF1 MITIGATES RETINAL GANGLION CELL APOPTOSIS IN GLAUCOMA BY REGULATING THE Nrf2/HO-1 PATHWAY.

Published in:

Clinical & Investigative Medicine, 2025, v. 48, n. 2, p. 47, doi. 10.3138/CIM-2025-0119

By:

Ping Jiang;
Kongliang Sun;
Yaoyin Ma;
Xuesha Shi;
Hanjun Dai;
Zhi Li

Publication type:

Article

miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02139-z

By:

Pan, Wen;
Tan, Ying;
Chen, Xiaohong;
Zeng, Li;
Lv, Yuetong;
Yang, Jinlin

Publication type:

Article

Curcumin preserves bone health compromised by diabetes by inhibiting osteoporosis through regulation of the SIRT3/FoxO3a signalling pathway.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-15165-8

By:

Mohammad, Osama H.;
Yang, Shuaijie;
Ji, Wei;
Ma, Hongdong;
Tao, Ran

Publication type:

Article

Exosomal LncRNA SCAMP1-AS1 enhances osteosarcoma malignancy by regulating the LKB1-AMPK signaling pathway.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-15125-2

By:

Li, Yanxia;
Zou, Xiuqi;
Feng, Xiaomin;
Xia, Jing;
Wu, Zhifeng;
Ma, Haili

Publication type:

Article

Cellular dynamics and signalling mechanisms in dentine repair: A narrative review.

Published in:

International Endodontic Journal, 2025, v. 58, n. 9, p. 1354, doi. 10.1111/iej.14261

By:

Rajasekar, Vidhyashree;
Abdalla, Mohamed Mahmoud;
Neelakantan, Prasanna;
Yiu, Cynthia K. Y.

Publication type:

Article

Nestin in multiple myeloma: emerging insights into a potential therapeutic target.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1596928

By:

Wu, Yingmiao;
Luo, Ji;
Zhou, Yue;
Lin, Jiaoya;
Wu, Yajie;
Zheng, Shuai;
Chen, Jiao;
Che, Feifei;
Wang, Qiang;
Zhong, Ling

Publication type:

Article

The kinase ERK plays a conserved dominant role in the heterogeneity of epithelial-mesenchymal transition in pancreatic cancer cells.

Published in:

Science Signaling, 2025, v. 18, n. 899, p. 1, doi. 10.1126/scisignal.ads7002

By:

Barbeau, Michelle C.;
Brown, Brooke A.;
Adair, Sara J.;
Bauer, Todd W.;
Lazzara, Matthew J.

Publication type:

Article

Retinopathy of Prematurity—Targeting Hypoxic and Redox Signaling Pathways - Editor’s Response.

Published in:

Neonatology Today, 2025, v. 20, n. 7, p. 79

By:

Goldstein, Mitchell

Publication type:

Article

Retinopathy of Prematurity—Targeting Hypoxic and Redox Signaling Pathways.

Published in:

Neonatology Today, 2025, v. 20, n. 7, p. 78

By:

Petrosyan, Aelita

Publication type:

Article

The Mechanism of Qidongning Formula Preventing Lung Cancer Based on Network Pharmacology and Experimental Validation.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 4, p. 406, doi. 10.1007/s11094-025-03408-x

By:

Wang, Jinpei;
Jiang, Qi;
Zheng, Santing;
Yang, Xiaoli

Publication type:

Article

Unlocking the therapeutic potential of the STING signaling pathway in anti-tumor treatment.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01838-1

By:

Li, Jinghui;
Yang, Haoqiang;
Zhu, Meiling;
Zhang, Pengyu;
Liu, Yang;
Niu, Yiting;
Zhou, Tao;
Li, Yanjun

Publication type:

Article

Flower jasmonates control fertility but are largely disconnected from defense metabolites in reproductive tissues of rice.

Published in:

Journal of Experimental Botany, 2025, v. 76, n. 10, p. 2846, doi. 10.1093/jxb/eraf073

By:

Fukumoto, Kaori;
Hojo, Yuko;
Nakatani, Hiroko;
Wari, David;
Shinya, Tomonori;
Galis, Ivan

Publication type:

Article

Investigating how reproductive traits in rice respond to abiotic stress Open Access.

Published in:

Journal of Experimental Botany, 2025, v. 76, n. 8, p. 2064, doi. 10.1093/jxb/eraf031

By:

Liberatore, Claudia Maria;
Biancucci, Marco;
Ezquer, Ignacio;
Gregis, Veronica;
Marzo, Maurizio Di

Publication type:

Article

Ethylene signaling is essential for mycorrhiza-induced resistance against chewing herbivores in tomato Open Access.

Published in:

Journal of Experimental Botany, 2025, v. 76, n. 7, p. 2005, doi. 10.1093/jxb/eraf053

By:

Lidoy, Javier;
Rivero, Javier;
Ramšak, Živa;
Petek, Marko;
Križnik, Maja;
Flors, Victor;
Lopez-Raez, Juan A;
Martinez-Medina, Ainhoa;
Gruden, Kristina;
Pozo, Maria J

Publication type:

Article

Transcriptional regulation of development by SMAX1-LIKE proteins – targets of strigolactone and karrikin/KAI2 ligand signaling.

Published in:

Journal of Experimental Botany, 2025, v. 76, n. 7, p. 1888, doi. 10.1093/jxb/eraf027

By:

Chang, Sun Hyun;
George, Wesley;
Nelson, David C

Publication type:

Article

Diverse roles of phytohormonal signaling in modulating plant–virus interactions.

Published in:

Journal of Experimental Botany, 2025, v. 76, n. 7, p. 1921, doi. 10.1093/jxb/erae468

By:

Sharma, Shambhavi;
Prasad, Manoj

Publication type:

Article

The heat shock response in plants: new insights into modes of perception, signaling, and the contribution of hormones Open Access.

Published in:

Journal of Experimental Botany, 2025, v. 76, n. 7, p. 1970, doi. 10.1093/jxb/erae419

By:

Dündar, Gönül;
Ramirez, Veronica E;
Poppenberger, Brigitte

Publication type:

Article

Five unaddressed questions about cytokinin biosynthesis Open Access.

Published in:

Journal of Experimental Botany, 2025, v. 76, n. 7, p. 1941, doi. 10.1093/jxb/erae348

By:

Sakakibara, Hitoshi

Publication type:

Article

The interplay between physical exercise and autophagy signaling in brain health, neurodegenerative diseases and aging.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1579208

By:

Gao, Bo;
Wang, Li;
Gong, Jian;
Zhu, Zehua;
Liu, Qi;
Yuan, Han;
Wang, Haitao

Publication type:

Article

Identification of candidate immunity biomarkers associated with age-related variations in osteoclast activity in a mouse model of orthodontic tooth movement.

Published in:

BMC Oral Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12903-025-06688-7

By:

Zhang, Rui;
Yang, Kai;
He, Lulu;
Chen, Zhen;
Li, Yuhong;
Huang, Shengfu

Publication type:

Article

Neural signature of chronic migraine mice model and related photophobia in the primary visual cortex.

Published in:

Journal of Headache & Pain, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s10194-025-02123-y

By:

Zhang, Kai-Bo;
Peng, Cheng;
Liu, Zhen;
Zhao, Sheng-Lin;
Zhu, Chen-Lu;
Wu, Shou-Yi;
Wang, Tian-Xiao;
Li, Zhi-Lei;
Gao, Jing-Gui;
Xu, Yun-Hao;
Fan, Tian-Hua;
Xie, Hong;
Guan, Ji-Song;
Wang, Yong-Gang

Publication type:

Article

Substrate-selective COX-2 inhibition by IMMA attenuates posttraumatic headache via endocannabinoid modulation and neuroinflammatory suppression.

Published in:

Journal of Headache & Pain, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s10194-025-02116-x

By:

Wen, Jie;
Tanaka, Mikiei;
Zhang, Yumin

Publication type:

Article

MYB/AKT3 axis is a key driver of ovarian cancer growth, aggressiveness, and chemoresistance.

Published in:

Journal of Ovarian Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13048-025-01761-9

By:

Vikramdeo, Kunwar Somesh;
Miree, Orlandric;
Anand, Shashi;
Sharma, Amod;
Srivastava, Sanjeev Kumar;
Singh, Seema;
Rocconi, Rodney P;
Singh, Ajay Pratap

Publication type:

Article

Isolation of phytochemicals and exploration the mechanism of Dolichandrone spathacea in the treatment of chronic bronchitis by integrating network pharmacology, molecular docking, and experimental validation.

Published in:

Botanical Studies, 2025, v. 66, n. 1, p. 1, doi. 10.1186/s40529-025-00464-0

By:

Nguyen, Dang-Khoa;
Liu, Ta-Wei;
Chu, Man-Hsiu;
Huynh, Quoc-Dung Tran;
Duong, Truc-Ly Thi;
Phan, Thuy-Tien Thi;
Huynh, Duyen Thi My;
Wang, Yun-Han;
Wang, Shu-Mei;
Hsu, Su-Jung;
Lee, Ching-Kuo

Publication type:

Article

The mitochondrial hub gene UCHL1 May serve as a potential biomarker for diagnosing diabetic cardiomyopathy: a comprehensive integration of biological pathways.

Published in:

BMC Medical Genomics, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12920-025-02199-0

By:

Gao, Chengjie;
Tao, Yijing;
Qian, Da;
Zhou, Yafeng

Publication type:

Article

Zinc‐Directed Coordination Network Hydrogels for A20‐Mediated Inflammation Modulation and Enhanced Axonal Regeneration in Spinal Cord Injury.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 32, p. 1, doi. 10.1002/adfm.202422906

By:

Zhang, Jianye;
Gao, Yisheng;
Zhang, Miao;
Zhao, Yue;
Wang, Chunxue;
Gong, Jiahuan;
Ding, Supeng;
Liu, Mengke;
Zhao, Xueying;
Wu, Bingxin;
Yang, Yumin;
Zhao, Yahong

Publication type:

Article

Systematic analysis of the interaction mechanism between platelets and coronary heart disease: from molecular pathways to new strategies for plant based antiplatelet therapy.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1586265

By:

Liao, Li;
Li, Xiaoxuan;
Xu, Hong;
Tang, Jing;
Li, Bo;
Tang, Yan;
Xie, Fang

Publication type:

Article

Alterations in Signaling Pathways and Therapeutic Strategies of Traditional Chinese Medicine in Granulomatous Lobular Mastitis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 9185, doi. 10.2147/JIR.S535195

By:

Zhang, Mengdi;
Pu, Dongqing;
Meng, Feifei;
Shi, Guangxi;
Li, Jingwei

Publication type:

Article

Extracellular domain shedding of NOTCH3 during endocytosis associated with heterogeneity between different CADASIL mutant activation mechanisms.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02362-1

By:

Hosseini-Alghaderi, Samira;
Baron, Martin

Publication type:

Article

Astrocyte-derived CXCL10 exacerbates endothelial cells pyroptosis and blood–brain barrier disruption via CXCR3/cGAS/AIM2 pathway after intracerebral hemorrhage.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02658-8

By:

Sheng, Wenqianjun;
Wu, Zhangyi;
Wei, Jingyan;
Wang, Jun;
Zhang, Shengfan;
Ding, Zhiquan;
Zhong, Jinhao;
Deng, Dexian;
Zhong, Zhenzhong;
Yin, Yunong;
Li, Yulong;
Wang, Qinghua

Publication type:

Article

松萝酸抗肿瘤的分子机制研究进展及治疗应用的挑战与对策.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 784, doi. 10.3872/j.issn.1007-385x.2025.07.016

By:

屈林源;
王姝涵;
杨今实

Publication type:

Article

靶向 PD-1/PD-L1 通路的联合治疗策略在软骨肉瘤治疗中研究和应用进展.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 777, doi. 10.3872/j.issn.1007-385x.2025.07.015

By:

徐邦哲;
王策

Publication type:

Article

IL-33/ST2信号通路在胃肠道肿瘤中作用及其机制的研究进展.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 765, doi. 10.3872/j.issn.1007-385x.2025.07.013

By:

焦静;
蒋敬庭

Publication type:

Article

DUSP26 通过抑制 TGF-β1/SMAD 信号通路抑制肺腺癌 A549 细胞增殖、迁移和侵袭.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 738, doi. 10.3872/j.issn.1007-385x.2025.07.009

By:

罗锋珩;
吴敏;
周珊;
肖亚南;
占志强

Publication type:

Article

lncRNA SOX2-OT调控miR-215-5p/NOB1通路抑制结直肠癌HCT-116 细胞增殖和迁移.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 731, doi. 10.3872/j.issn.1007-385x.2025.07.008

By:

刘丹;
程海林;
罗剑锋

Publication type:

Article

川楝素经 AKT/mTOR 通路下调 HIF1A 表达抑制食管鳞状细胞癌 KYSE150 细胞的恶性生物学行为.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 723, doi. 10.3872/j.issn.1007-385x.2025.07.007

By:

楚月明;
朱茂菲;
蒋杭遇;
袁强;
李兴;
刘康;
李林

Publication type:

Article

基于 WGCNA 揭示贝沙罗汀通过调控 c-Myc 通路抑制双打击淋巴瘤的机制.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 716, doi. 10.3872/j.issn.1007-385x.2025.07.006

By:

何田田;
李泓毅;
耿杰;
侯传东;
张虹;
张辉;
赵鹏;
卢学春;
贺培风

Publication type:

Article

2',4'-二羟基查尔酮通过调控 miR-7-5p 诱导自噬抑制结直肠癌细胞增殖和迁移.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 7, p. 698, doi. 10.3872/j.issn.1007-385x.2025.07.004

By:

苏朝霞;
王南苗;
陈丹;
韩有艳;
毕遥;
王彤;
安仁波;
朴英实;
任香善;
李文静

Publication type:

Article

Novel pyran-based anti-inflammatory agents: design, synthesis, and mechanistic studies in LPS-stimulated macrophages.

Published in:

Applied Biological Chemistry, 2025, v. 68, n. 1, p. 1, doi. 10.1186/s13765-025-01018-5

By:

He, Mei Tong;
Kim, Sung Jin;
Le, Viet Duc;
Min, Su Ji;
Lee, Heesu;
Lee, Jae Wook;
Shin, Myoung-Sook

Publication type:

Article

Correction to: Triamcinolone Acetonide Protects Against Light-Induced Retinal Degeneration by Activating Anti-Inflammatory STAT6/Arg1 Signaling in Microglia.

Published in:

2025

By:

Tang, Xiangcheng;
Liu, Wei;
Liang, Jia;
Zhu, Xingfei;
Ge, Xiangyu;
Fang, Dong;
Ling, Lirong;
Yuan, Fanglan;
Zeng, Kun;
Chen, Qingshan;
Zhang, Guoming;
Gong, Lili;
Zhang, Shaochong

Publication type:

Correction Notice

IL-17A-Induced Redox Imbalance and Inflammatory Responses in Mice Lung via Act1-TRAF6-IKBα Signaling Pathway: Implications for Lung Disease Pathogenesis.

Published in:

Inflammation, 2025, v. 48, n. 4, p. 2417, doi. 10.1007/s10753-024-02199-9

By:

Panda, Ekta Swarnamayee;
Gautam, Avtar Singh;
Pandey, Shivam Kumar;
Singh, Rakesh Kumar

Publication type:

Article

NOD3 Reduces Sepsis-Induced Acute Lung Injury by Regulating the Activation of NLRP3 Inflammasome and the Polarization of Alveolar Macrophages.

Published in:

Inflammation, 2025, v. 48, n. 4, p. 2395, doi. 10.1007/s10753-024-02197-x

By:

Zhao, Yue;
Wu, Yongran;
Qu, Lianlian;
Hu, Yingying;
Sun, Shengwen;
Yao, Ruishan;
Li, Ruiting

Publication type:

Article

Triamcinolone Acetonide Protects Against Light-Induced Retinal Degeneration by Activating Anti-Inflammatory STAT6/Arg1 Signaling in Microglia.

Published in:

2025

By:

Tang, Xiangcheng;
Liu, Wei;
Liang, Jia;
Zhu, Xingfei;
Ge, Xiangyu;
Fang, Dong;
Ling, Lirong;
Yuan, Fanglan;
Zeng, Kun;
Chen, Qingshan;
Zhang, Guoming;
Gong, Lili;
Zhang, Shaochong

Publication type:

Letter

Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling.

Published in:

Journal of Physiology, 2025, v. 603, n. 15, p. 4329, doi. 10.1113/JP286665

By:

Kostritskaia, Yulia;
Pervaiz, Sumaira;
Klemmer, Anna;
Klüssendorf, Malte;
Stauber, Tobias

Publication type:

Article

EP300/HIF-1 pathway: the key to sacubitril valsartan sodium alleviating myocardial hypoxia injury.

Published in:

Xenobiotica, 2025, v. 55, n. 6, p. 478, doi. 10.1080/00498254.2025.2528516

By:

Fang, Jianyun;
Yang, Dan;
Liu, Fan;
Xiao, Rong;
Liang, Youqing;
Tang, Jiong

Publication type:

Article

Moxibustion Improves Mitochondrial Energy Metabolism in Rats with Chronic Heart Failure via AMPK/PGC-1α Pathway Activation.

Published in:

Acupuncture & Electro-Therapeutics Research, 2025, v. 49, n. 3, p. 103, doi. 10.1177/03601293251346488

By:

Li, Qingling;
Pan, Liu;
Xia, Ran;
Gao, Bing;
Jia, Xuezhao;
Ma, Qiang;
Wang, Jing

Publication type:

Article

Analysis of Fibroblast Growth Factor 2 Impact and Mechanism on Broncho-Pulmonary Dysplasia.

Published in:

International Archives of Allergy & Immunology, 2025, v. 186, n. 8, p. 769, doi. 10.1159/000543105

By:

Lu, Ling;
Liu, Ye-Dan;
Liu, Dong-Yun;
Jin, Rong;
Qu, Zheng-Hai

Publication type:

Article

Transcriptional enhanced associate domain factor 1 regulates cortactin-binding protein 2 N-terminal-like to control cell apoptosis in thyroid cancer.

Published in:

CytoJournal, 2025, v. 22, p. 1, doi. 10.25259/Cytojournal_140_2024

By:

Ma, Qian;
Zhang, Liyong;
Jiang, Shan;
Zhao, Wenxin

Publication type:

Article

Regulator of chromosome condensation 1 and broad-complex, tramtrack and bric a brac domain-containing protein is involved in ovarian cancer growth and drug resistance.

Published in:

CytoJournal, 2025, v. 22, p. 1, doi. 10.25259/Cytojournal_268_2024

By:

Zhao, Gaowa;
Xiao, Xiaochao;
Song, Limeng;
Qi, Bangruo

Publication type:

Article

1α, 25-dihydroxyvitamin D3 attenuates tumor necrosis factor-α-induced endothelial cell injury by modulating the tumor necrosis factor-α/nuclear factor kappa-B pathway.

Published in:

CytoJournal, 2025, v. 22, p. 1, doi. 10.25259/Cytojournal_220_2024

By:

Xia, Yangyang;
Liu, Sixiu;
Shao, Qiuyuan;
Feng, Yuan;
Jin, Bo;
Zhang, Qingyan

Publication type:

Article