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- Title
Serum SPARC and matrix metalloproteinase-2 and metalloproteinase-9 concentrations after bariatric surgery in obese adults.
- Authors
Lee, Yeon Ji; Heo, Yoon-Seok; Park, Hye Soon; Lee, Seoung Hee; Lee, Seul Ki; Jang, Yeon Jin
- Abstract
Remodeling of the extracellular matrix (ECM) of adipose tissue is regarded as part of the pathophysiology of obesity. Secreted protein acidic and rich in cysteine (SPARC) was the first ECM protein described in adipose tissue. Matrix metalloproteinases (MMPs) also play a role in ECM remodeling, and MMP-2 and MMP-9 may be associated with abnormal ECM metabolism. Here, we investigated changes in serum SPARC, MMP-2, and MMP-9 concentrations after bariatric surgery in obese adults.
- Publication
Obesity surgery, 2014, Vol 24, Issue 4, p604
- ISSN
1708-0428
- Publication type
Journal Article
- DOI
10.1007/s11695-013-1111-z