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Title
Weight loss after Roux-en-Y gastric bypass in obese patients heterozygous for MC4R mutations.
Authors
Aslan, Ivy R; Campos, Guilherme M; Calton, Melissa A; Evans, Daniel S; Merriman, Raphael B; Vaisse, Christian
Abstract
Heterozygous mutations in melanocortin-4 receptor (MC4R) are the most frequent genetic cause of obesity. Bariatric surgery is a successful treatment for severe obesity. The mechanisms of weight loss after bariatric surgery are not well understood.