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- Title
Placebo adherence and its association with morbidity and mortality in the studies of left ventricular dysfunction.
- Authors
Avins, Andrew L; Pressman, Alice; Ackerson, Lynn; Rudd, Peter; Neuhaus, John; Vittinghoff, Eric
- Abstract
A provocative finding from several double-blind clinical trials has been the association between greater adherence to placebo study medication and better health outcomes. We used data from the Studies of Left Ventricular Dysfunction (SOLVD) Treatment Trial (SOLVD-TT) and the SOLVD Prevention Trial (SOLVD-PT) to examine whether such associations could be validated and to examine several sources of bias and potential confounding.
- Publication
Journal of general internal medicine, 2010, Vol 25, Issue 12, p1275
- ISSN
1525-1497
- Publication type
Journal Article
- DOI
10.1007/s11606-010-1477-8