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- Title
Comparison of three dimeric 18F-AlF-NOTA-RGD tracers.
- Authors
Guo, Jinxia; Lang, Lixin; Hu, Shuo; Guo, Ning; Zhu, Lei; Sun, Zhongchan; Ma, Ying; Kiesewetter, Dale O; Niu, Gang; Xie, Qingguo; Chen, Xiaoyuan
- Abstract
RGD peptide-based radiotracers are well established as integrin αvβ3 imaging probes to evaluate tumor angiogenesis or tissue remodeling after ischemia or infarction. In order to optimize the labeling process and pharmacokinetics of the imaging probes, we synthesized three dimeric RGD peptides with or without PEGylation and performed in vivo screening.
- Publication
Molecular imaging and biology, 2014, Vol 16, Issue 2, p274
- ISSN
1860-2002
- Publication type
Journal Article
- DOI
10.1007/s11307-013-0668-1