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- Title
Comorbid anxiety in bipolar disorder alters treatment and prognosis.
- Authors
El-Mallakh, Rif S; Hollifield, Michael
- Abstract
Mood disorders in general, and bipolar disorder in particular, are unique among the psychiatric conditions in that they are associated with extraordinarily high rates of comorbidity with a multitude of psychiatric and medical conditions. Among all the potential comorbidities, co-occurring anxiety disorders stand out due to their very high prevalence. Outcome in bipolar illness is worse in the presence of a comorbid anxiety disorder. The coexistence of an anxiety disorder presents a particularly difficult challenge in the treatment of bipolar illness since antidepressants, the mainstay of pharmacologic treatments for anxiety, may adversely alter the course of manic-depression. Identification of anxiety disorders in bipolar patients is important. The treatment plan needs to balance the potential benefit and harm of antidepressant administration.
- Publication
The Psychiatric quarterly, 2008, Vol 79, Issue 2, p139
- ISSN
0033-2720
- Publication type
Journal Article
- DOI
10.1007/s11126-008-9071-5