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- Title
Delivery of water-soluble drugs using acoustically triggered perfluorocarbon double emulsions.
- Authors
Fabiilli, Mario L; Lee, James A; Kripfgans, Oliver D; Carson, Paul L; Fowlkes, J Brian
- Abstract
Ultrasound can be used to release a therapeutic payload encapsulated within a perfluorocarbon (PFC) emulsion via acoustic droplet vaporization (ADV), a process whereby the PFC phase is vaporized and the agent is released. ADV-generated microbubbles have been previously used to selectively occlude blood vessels in vivo. The coupling of ADV-generated drug delivery and occlusion has therapeutically synergistic potentials.
- Publication
Pharmaceutical research, 2010, Vol 27, Issue 12, p2753
- ISSN
1573-904X
- Publication type
Journal Article
- DOI
10.1007/s11095-010-0277-5