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- Title
In vitro-in vivo correlations of scalable PLGA-risperidone implants for the treatment of schizophrenia.
- Authors
Amann, Laura C; Gandal, Michael J; Lin, Robert; Liang, Yuling; Siegel, Steven J
- Abstract
Nonadherence to antipsychotic medications is a major obstacle preventing optimal outcomes for patients with schizophrenia. Extended release systems exist in the form of depot injections, but these formulations exhibit several disadvantages. To address these concerns, we previously demonstrated proof of concept for an antipsychotic implant containing risperidone and the biodegradable polymer poly(lactic-co-glycolic) acid (PLGA).
- Publication
Pharmaceutical research, 2010, Vol 27, Issue 8, p1730
- ISSN
1573-904X
- Publication type
Journal Article
- DOI
10.1007/s11095-010-0152-4