We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prolonged survival of neoplastic meningitis from breast cancer with letrozole and intrathecal methotrexate: a case report.
- Authors
Peroukides, Stavros; Onyenadum, Adimchi; Starakis, Ioannis; Koutras, Angelos; Makatsoris, Thomas; Bouboukas, George; Kalofonos, Haralabos
- Abstract
Neoplastic meningitis from breast cancer has a dismal prognosis and short survival. Treatment is based on the intrathecal administration of chemotherapeutic agents, cranial or craniospinal radiotherapy, and systemic chemotherapy. In this report we describe the case of a woman with neoplastic meningitis from breast carcinoma who developed an excellent response to letrozole combined with intrathecal methotrexate, resulting in long-term survival of more than 36 months. Based on the findings of this case report, we suggest that addition of letrozole to the standard therapeutic approach may be beneficial for some patients.
- Publication
Journal of neuro-oncology, 2011, Vol 101, Issue 3, p509
- ISSN
1573-7373
- Publication type
Journal Article
- DOI
10.1007/s11060-010-0268-8