Works matching DE "TUMOR microenvironment"

Results: 5000

Advances in Photoacoustic Imaging of Breast Cancer.

Published in:

Sensors (14248220), 2025, v. 25, n. 15, p. 4812, doi. 10.3390/s25154812

By:

Wu, Yang;
Huang, Keer;
Chen, Guoxiong;
Lin, Li

Publication type:

Article

Noninvasive Mapping of Extracellular Potassium in Breast Tumors via Multi-Wavelength Photoacoustic Imaging.

Published in:

Sensors (14248220), 2025, v. 25, n. 15, p. 4724, doi. 10.3390/s25154724

By:

Folz, Jeff;
Eido, Ahmad;
Gonzalez, Maria E.;
Caruso, Roberta;
Wang, Xueding;
Kleer, Celina G.;
Jo, Janggun

Publication type:

Article

Molecular Crosstalk Between RUNX2 and HIF-1α in Osteosarcoma: Implications for Angiogenesis, Metastasis, and Therapy Resistance.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7642, doi. 10.3390/ijms26157642

By:

Magar, Anuja Gajanan;
Morya, Vivek Kumar;
Noh, Kyu-Cheol

Publication type:

Article

Transcriptional Repression of CCL2 by K Ca 3.1 K + Channel Activation and LRRC8A Anion Channel Inhibition in THP-1-Differentiated M 2 Macrophages.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7624, doi. 10.3390/ijms26157624

By:

Matsui, Miki;
Kajikuri, Junko;
Kito, Hiroaki;
Yamaguchi, Yohei;
Ohya, Susumu

Publication type:

Article

A Bifunctional Anti-PD-1/TGF-β Fusion Antibody Restores Antitumour Immunity and Remodels the Tumour Microenvironment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7567, doi. 10.3390/ijms26157567

By:

Nan, Lidi;
Qin, Yuting;
Huang, Xiao;
Pan, Mingzhu;
Wang, Xiaomu;
Lv, Yanqing;
Sorensen, Annette;
Kang, Xiaoqiang;
Ling, Hong;
Zhang, Juan

Publication type:

Article

Metabolic Interactions in the Tumor Microenvironment of Classical Hodgkin Lymphoma: Implications for Targeted Therapy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7508, doi. 10.3390/ijms26157508

By:

Kurlapski, Michał;
Braczko, Alicja;
Dubiela, Paweł;
Walczak, Iga;
Kutryb-Zając, Barbara;
Zaucha, Jan Maciej

Publication type:

Article

Utility of Multicellular Spheroids for Investigating Mechanisms of Chemoresistance in Triple-Negative Breast Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7503, doi. 10.3390/ijms26157503

By:

Ncube, Keith N.;
van den Bout, Iman;
Willers, Clarissa;
Gouws, Chrisna;
Cordier, Werner

Publication type:

Article

Environmental Hazards and Glial Brain Tumors: Association or Causation?

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7425, doi. 10.3390/ijms26157425

By:

Ostrowski, Robert P.;
Acewicz, Albert;
He, Zhaohui;
Pucko, Emanuela B.;
Godlewski, Jakub

Publication type:

Article

Cancer Stem Cells in Melanoma: Drivers of Tumor Plasticity and Emerging Therapeutic Strategies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7419, doi. 10.3390/ijms26157419

By:

Sabău, Adrian-Horațiu;
Tinca, Andreea-Cătălina;
Niculescu, Raluca;
Cocuz, Iuliu Gabriel;
Cozac-Szöke, Andreea Raluca;
Lazar, Bianca Andreea;
Chiorean, Diana Maria;
Budin, Corina Eugenia;
Cotoi, Ovidiu Simion

Publication type:

Article

Variations in Circulating Tumor Microenvironment-Associated Proteins in Non-Muscle Invasive Bladder Cancer Induced by Mitomycin C Treatment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7413, doi. 10.3390/ijms26157413

By:

Gómez, Benito Blanco;
Casas-Nebra, Francisco Javier;
Pérez-Fentes, Daniel;
Bravo, Susana B.;
Rodríguez-Silva, Laura;
Núñez, Cristina

Publication type:

Article

IL-20 Subfamily Biological Effects: Mechanistic Insights and Therapeutic Perspectives in Cancer.

Published in:

2025

By:

Maggisano, Valentina;
D'Amico, Maria;
Aquila, Saveria;
Giordano, Francesca;
Battaglia, Anna Martina;
Chimento, Adele;
Biamonte, Flavia;
Russo, Diego;
Pezzi, Vincenzo;
Bulotta, Stefania;
De Amicis, Francesca

Publication type:

Abstract

Immunomodulatory Natural Products in Cancer Organoid-Immune Co-Cultures: Bridging the Research Gap for Precision Immunotherapy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7247, doi. 10.3390/ijms26157247

By:

Hong, Chang-Eui;
Lyu, Su-Yun

Publication type:

Article

Special Issue "Advances in Targeted Cancer Therapy and Mechanisms of Resistance—2nd Edition".

Published in:

2025

By:

Tang, Patrick Ming-Kuen;
Xian, Yan-Fang;
Zhang, Dongmei

Publication type:

Editorial

Pan-Cancer Computational Analysis of RKIP (PEBP1) and LKB1 (STK11) Co-Expression Highlights Distinct Immunometabolic Dynamics and Therapeutic Responses Within the Tumor Microenvironment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7145, doi. 10.3390/ijms26157145

By:

Skouradaki, Evangelia;
Zaravinos, Apostolos;
Panagopoulou, Maria;
Chatzaki, Ekaterini;
Dovrolis, Nikolas;
Baritaki, Stavroula

Publication type:

Article

PriorCCI: Interpretable Deep Learning Framework for Identifying Key Ligand–Receptor Interactions Between Specific Cell Types from Single-Cell Transcriptomes.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7110, doi. 10.3390/ijms26157110

By:

Kim, Hanbyeol;
Choi, Eunyoung;
Shim, Yujeong;
Kwon, Joonha

Publication type:

Article

The 3D Language of Cancer: Communication via Extracellular Vesicles from Tumor Spheroids and Organoids.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7104, doi. 10.3390/ijms26157104

By:

Campora, Simona;
Lo Cicero, Alessandra

Publication type:

Article

Roles of Peripheral Nerves in Tumor Initiation and Progression.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7064, doi. 10.3390/ijms26157064

By:

Giampietri, Claudia;
Pizzichini, Elisa;
Somma, Francesca;
Petrungaro, Simonetta;
De Santis, Elena;
Rahimi, Siavash;
Facchiano, Antonio;
Fabrizi, Cinzia

Publication type:

Article

Beyond the Walls of Troy: A Scoping Review on Pharmacological Strategies to Enhance Drug Delivery Across the Blood–Brain Barrier and Blood–Tumor Barrier.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7050, doi. 10.3390/ijms26157050

By:

Pinkiewicz, Miłosz;
Zaczyński, Artur;
Walecki, Jerzy;
Zawadzki, Michał

Publication type:

Article

Mechanistic modeling suggests stroma-targeting antibody-drug conjugates as an alternative to cancer-targeting in cases of heterogeneous target exspression.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 8, p. 1, doi. 10.1371/journal.pcbi.1012839

By:

Wood, N. Ezgi;
Cengiz, Anıl;
Gao, Ming;
Ratushny, Alexander V.;
Straube, Ronny

Publication type:

Article

Sequential treatment with PARPi and WEE1i enhances antitumor immune responses in preclinical models of ovarian cancer.

Published in:

Science Translational Medicine, 2025, v. 17, n. 811, p. 1, doi. 10.1126/scitranslmed.adu6989

By:

Jiao, Xiaofei;
Liu, Jiahao;
Wu, Yijie;
Zhong, Qing;
Zhu, Li;
Wang, Linghui;
Li, Huayi;
Xiang, Minghua;
Zhao, Xuejiao;
Zhao, Guangnian;
Mills, Gordon B.;
Ma, Ding;
Gao, Qinglei;
Fang, Yong

Publication type:

Article

Prognostic Implications of Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Published in:

Journal of Orofacial Sciences, 2025, v. 17, n. 1, p. 88, doi. 10.4103/jofs.jofs_29_25

By:

Surendran L, Surya;
Joseph, Anna Palliath;
Pillai, Varun B Raghavan;
Somaraj, Vinej;
Sudhakar, Sunjith;
Mohan, Amitha

Publication type:

Article

Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1610886

By:

Alaseem, Ali M.;
Aldali, Jehad A.;
Alasiri, Glowi;
Alhujaily, Muhanad;
AlHussaini, Khalid I.;
AlKhamees, Osama A.

Publication type:

Article

Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1555302

By:

Niu, Yanyan;
Liu, Xiaoyu;
Shi, Aixiu;
Tang, Danli;
Yao, Xiaodong;
Lu, Yan

Publication type:

Article

HPV infection and the immune microenvironment in cervical cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1645019

By:

Li, Yibo;
Deng, Jingui;
Liu, Yayong;
Yu, Shuangfeng

Publication type:

Article

Nanotechnology-driven platforms for extracellular vesicle analysis in tumor immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1632378

By:

Chen, Rui;
Kang, Qin;
Ning, Yudong

Publication type:

Article

Identification of a TIGIT-expressing CD8+ T cell subset as a potential prognostic biomarker in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1626367

By:

Cao, Shouli;
Wang, Meidan;
Sun, Weiqiang;
Ma, Zhibin;
Yang, Kun;
Li, Ting;
Zhu, Xuedan;
Pei, Yang;
Pan, Mingyue;
Wang, Liqun;
Ding, Honglin

Publication type:

Article

Unveiling B7/CD28 family proteins in hepatocellular carcinoma: insights into communication and prognostic significance.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1583597

By:

Cai, Yan;
Liu, Xiaodi;
He, Tao;
Xu, Yangming;
Chen, Shuxian;
Tan, Xianliang;
Wei, Shouchao;
Wu, Zimeng;
Xiao, Liying;
Luo, Baoming

Publication type:

Article

Advancing oral squamous cell carcinoma research: the evolving role of patient-derived cell lines, xenografts, and organoid models.

Published in:

3 Biotech, 2025, v. 15, n. 9, p. 1, doi. 10.1007/s13205-025-04472-6

By:

Upadhyay, Vinal;
Das, Sourav;
Nehru, Amisha;
Swetha, Uppalpati Sai;
Vatsa, Priyanka Patel;
Chamoli, Ambika;
Mandoli, Amit

Publication type:

Article

Fibroblast activation protein on human natural killer cells: insights from natural killer cell activation and crosstalk with cancer-associated fibroblasts.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 7, p. 1, doi. 10.1093/jleuko/qiaf103

By:

Rymenant, Yentl Van;
Groot, Anke de;
Dirkx, Laura;
Verhulst, Emile;
Loose, Joni De;
Pintelon, Isabel;
Verhezen, Tias;
Waele, Jorrit De;
Thys, Sofie;
Wever, Olivier De;
Tanc, Muhammet;
Caljon, Guy;
Veken, Pieter Van der;
Meester, Ingrid De

Publication type:

Article

Potential functions of TRPM2 and TRPM7 channels in the tumor microenvironment.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 7, p. 1, doi. 10.1093/jleuko/qiaf098

By:

Izaguirre-Hernández, Irma Yadira;
Sumoza-Toledo, Adriana

Publication type:

Article

Pre-ligand assembly domain-derived recombinant protein of TNFR2 inhibits the expansion of CD4+ Foxp3+ regulatory T cells.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 7, p. 1, doi. 10.1093/jleuko/qiaf087

By:

Li, Wen-Wei;
Li, Chuangen;
Yang, Yang;
Chen, Yibo;
Chen, Zhonghao;
Gao, Yang;
Wang, Yiru;
Liu, Tao;
Chen, Xin;
Chou, Chon-Kit

Publication type:

Article

The role of tumor-associated neutrophils in the pathogenesis of recurrent respiratory papillomatosis.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 7, p. 1, doi. 10.1093/jleuko/qiaf055

By:

Xiao, Yang;
Niu, Zijie;
Ma, Lijing;
Wang, Jun

Publication type:

Article

Intratumoral Heterogeneity Scores as Predictors of Invasiveness in Lung Adenocarcinoma Presenting as Pure Ground-Glass Nodules: Insights from Explainable Machine Learning-Based Ternary Classification Models.

Published in:

Technology in Cancer Research & Treatment, 2025, p. 1, doi. 10.1177/15330338251365985

By:

Peng, Wang;
Qi, Wanyin;
Li, Yunhua;
Zhang, Sanhong;
Long, Juan

Publication type:

Article

High oxidative phosphorylation represented by UQCRFS1 marks CD8 + tumor-infiltrating lymphocytes exhaustion in diffuse large B-cell lymphoma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00684-1

By:

Yang, Yiming;
Shu, Yaqi;
Qin, Zujun;
Zeng, Yi;
Chen, Kexin;
Liu, Xin;
Jian, Shunhai;
Zhu, Qiqi

Publication type:

Article

GPER1 is involved in shaping tumor immune microenvironment and its expression is decreased in NSCLC tumorigenesis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-15405-x

By:

Li, Zhenhua;
Xie, Chao;
Cui, Jingjing;
Xu, Hui;
Li, Dingbiao

Publication type:

Article

Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1610886

By:

Alaseem, Ali M.;
Aldali, Jehad A.;
Alasiri, Glowi;
Alhujaily, Muhanad;
AlHussaini, Khalid I.;
AlKhamees, Osama A.

Publication type:

Article

Fluorescence lifetime imaging microscopy approach reveals quantitative signatures for hepatocellular carcinoma diagnosis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1598334

By:

Li, Lingyun;
Wang, Aoshan;
Liu, Xiongqing;
Wang, Ganlu;
Xu, Shanjie;
Li, Changjiang;
Wu, Wenzhong;
Zhang, Xiaoying;
He, Zhendan;
Qiu, Huiling;
Peng, Xiao;
Yan, Wei;
Qu, Junle

Publication type:

Article

Identification of a TIGIT-expressing CD8+ T cell subset as a potential prognostic biomarker in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1626367

By:

Cao, Shouli;
Wang, Meidan;
Sun, Weiqiang;
Ma, Zhibin;
Yang, Kun;
Li, Ting;
Zhu, Xuedan;
Pei, Yang;
Pan, Mingyue;
Wang, Liqun;
Ding, Honglin

Publication type:

Article

Target neutrophil heterogeneity and plasticity in cancer.

Published in:

Journal of Hematology & Oncology, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13045-025-01731-0

By:

Feng, Ye;
Liu, Guang;
Li, Haiqing;
Cheng, Lin

Publication type:

Article

The molecular landscape of glioblastoma-associated epilepsy.

Published in:

Journal of Molecular Medicine, 2025, v. 103, n. 8, p. 923, doi. 10.1007/s00109-025-02567-4

By:

Scheffel, Thamiris Becker;
Diz, Fernando Mendonça;
Wieck, Andréa;
Begnini, Karine Rech;
da Costa, Jaderson Costa

Publication type:

Article

Unlocking the therapeutic potential of the STING signaling pathway in anti-tumor treatment.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01838-1

By:

Li, Jinghui;
Yang, Haoqiang;
Zhu, Meiling;
Zhang, Pengyu;
Liu, Yang;
Niu, Yiting;
Zhou, Tao;
Li, Yanjun

Publication type:

Article

Integrative bulk RNA analysis unveils immune evasion mechanisms and predictive biomarkers of osimertinib resistance in non-small cell lung cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02529-9

By:

Shi, Ling;
Qiu, Feng;
Shi, Chao;
Zhang, Guohua;
Yu, Feng

Publication type:

Article

Unravelling inflammation-driven mechanisms in hepatocellular carcinoma: therapeutic targets and potential interventions.

Published in:

Egyptian Liver Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s43066-025-00446-8

By:

Sen, Dhrubajyoti;
Bisht, Sonia;
Gupta, Sangeetha

Publication type:

Article

Advances in ORMDL Research in Malignant Tumors: A Review.

Published in:

OncoTargets & Therapy, 2025, v. 18, p. 821, doi. 10.2147/OTT.S537194

By:

Wang, Hao;
Yi, Zhongquan;
Yan, Song;
Wang, Yihao;
Zhang, Weisong;
Guo, Rongqi;
Li, Yangyang;
Wang, Rui;
Li, Heng;
Li, Xia;
Song, JianXiang

Publication type:

Article

GGTLC1 Is a Prognostic Biomarker in Renal Clear Cell Carcinoma.

Published in:

International Journal of Genomics, 2025, v. 2025, p. 1, doi. 10.1155/ijog/7524935

By:

Li, Shi;
Shi, Lijun;
Tao, Xiaofeng;
Yu, Guanghai;
Wang, Jianbo;
Sharma, Priyanka

Publication type:

Article

Harnessing intratumoral microbiota: new horizons in immune microenvironment and immunotherapy.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06916-2

By:

Zhang, Jinhe;
You, Zinan;
Li, Xinqiao;
Hu, Jinpeng;
Li, Jiamu;
Jing, Zhitao

Publication type:

Article

Nonhistone lactylation: A hub for tumour metabolic reprogramming and epigenetic regulation.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06813-8

By:

Zhang, Dawei;
Liang, Changming;
Wu, Chengwei;
Hawanga, Michael;
Wan, Senlin;
Xu, Lishuai;
Zhang, Xu;
Liu, Yongchun;
Hu, Fangshuai;
Wang, Mengyun;
Wang, Xiaoming;
Xu, Li;
Huang, Xiaoxu

Publication type:

Article

Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03657-8

By:

Gupta, Tanvi;
Wu, Shang-Rung;
Chang, Li-Chan;
Lin, Forn-Chia;
Shan, Yan-Shen;
Yeh, Chen-Sheng;
Su, Wen-Pin

Publication type:

Article

Targeting cytokine and chemokine signaling pathways for enhancing chemo-sensitivity in colorectal cancer.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02235-7

By:

Li, Shisen;
Xie, Mianjiao;
Du, Yongtao;
Tan, Zhaobang

Publication type:

Article

Multipath ROS Storm and Immune Activation via Sulfur Vacancy‐Optimized ZnIn2S4 Nanosheets for Piezocatalytic Tumor Therapy.

Published in:

Angewandte Chemie, 2025, v. 137, n. 33, p. 1, doi. 10.1002/ange.202507502

By:

Yang, Mingkai;
Ding, Binbin;
Ma, Xinyu;
Li, Jing;
Han, Di;
Liu, Sainan;
Liu, Zhendong;
Tan, Jia;
Chen, Hao;
Zheng, Pan;
Ma, Ping'an;
Lin, Jun

Publication type:

Article