Works matching DE "CELLULAR aging"

Results: 5000

Chemotherapy (Etoposide)-Induced Intermingling of Heterochromatin and Euchromatin Compartments in Senescent PA-1 Embryonal Carcinoma Cells.

Published in:

Cancers, 2025, v. 17, n. 15, p. 2480, doi. 10.3390/cancers17152480

By:

Bayer, Marc;
Zajakina, Jaroslava;
Schäfer, Myriam;
Salmina, Kristine;
Rumnieks, Felikss;
Jansons, Juris;
Bestvater, Felix;
Kurg, Reet;
Erenpreisa, Jekaterina;
Hausmann, Michael

Publication type:

Article

Anticancer Activity of Vitex agnus-castus Seed Extract on Gastric Cancer Cells.

Published in:

Nutrients, 2025, v. 17, n. 15, p. 2564, doi. 10.3390/nu17152564

By:

Türksoy-Terzioğlu, Özlem;
Tosya, Feyza;
Çelik, Ayşe Büşranur;
Bölek, Sibel;
Gülüm, Levent;
Terzioğlu, Gökhan;
Tutar, Yusuf

Publication type:

Article

Multi-omics and experimental validation studies reveal key biomarkers of cellular senescence in diabetic retinopathy.

Published in:

Diabetology & Metabolic Syndrome, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13098-025-01899-y

By:

Li, Jinju;
Yang, Hao;
Lin, Yixuan;
Fang, Zhaohui

Publication type:

Article

Multi-Omics Analysis and Validation of Cell Senescence-Related Genes Associated with Non-Alcoholic Fatty Liver Disease.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 8821, doi. 10.2147/JIR.S525168

By:

Gong, Jianhua;
Qin, Zhijie;
Xiao, Yihao;
Li, Jixue;
Wang, Qing;
Lei, Liping;
Li, Jiangfa

Publication type:

Article

Integrated Analysis of Ferroptosis- and Cellular Senescence-Related Biomarkers in Atherosclerosis Based on Machine Learning and Single-Cell Sequencing Data.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 9283, doi. 10.2147/JIR.S529581

By:

Qi, Xiang;
Cao, Shan;
Chen, Jian;
Yin, XiaoLei

Publication type:

Article

Perceived stress and allostatic load: Results from the All of Us Research Program.

Published in:

PLoS ONE, 2025, v. 20, n. 8, p. 1, doi. 10.1371/journal.pone.0330106

By:

Morley, Faith;
Mount, Lauren;
An, Anjile;
Phillips, Erica;
Tamimi, Rulla M.;
Kensler, Kevin H.

Publication type:

Article

Cellular Senescence Contributes to Colonic Barrier Integrity Impairment Induced by Toxoplasma gondii Infection.

Published in:

Inflammation, 2025, v. 48, n. 4, p. 2600, doi. 10.1007/s10753-024-02213-0

By:

Huang, Yingting;
Zhou, Yumeng;
He, Zhicheng;
Yang, Jiayi;
Gu, Jianqi;
Cui, Bingqian;
Li, Siyu;
Deng, Heng;
Zhao, Wendi;
Yang, Xiaoying;
Sun, Fenfen;
He, Cheng;
Pan, Wei

Publication type:

Article

Cellular senescence in cancer: from mechanism paradoxes to precision therapeutics.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02419-2

By:

Feng, Tiejun;
Xie, Fuda;
Lee, Leo M.Y.;
Lin, Zhiqiang;
Tu, Yifan;
Lyu, Yang;
Yu, Peiyao;
Wu, Jialin;
Chen, Bonan;
Zhang, Ge;
Tse, Gary M.K.;
To, Ka Fai;
Kang, Wei

Publication type:

Article

Cuttings from adult African mahogany individuals through tissue rejuvenation/reinvigoration.

Published in:

3 Biotech, 2025, v. 15, n. 9, p. 1, doi. 10.1007/s13205-025-04463-7

By:

dos Santos Azevedo, Cassia;
Faria, Júlio Cézar Tannure;
Caldeira, Marcos Vinicius Winckler;
de Oliveira Godinho, Tiago;
dos Santos, Heloisa Oliveira;
Pereira, Wilson Vicente Souza;
Gomes, Gabriel Soares Lopes;
Momolli, Dione Richer;
de Moura, Cristiane Coelho;
Atala, Laura Ribeiro

Publication type:

Article

Conserved and unique features of terminal telomeric sequences in ALTpositive cancer cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.106657

By:

Azeroglu, Benura;
Wei Wu;
Pavani, Raphael;
Sandhu, Ranjodh Singh;
Matsumoto, Tadahiko;
Nussenzweig, André;
Lazzerini-Denchi, Eros

Publication type:

Article

Inhibition of SIRT3 by a specific inhibitor induces cellular senescence and growth arrest of ovarian granulosa cell tumor via p53 and NF-κB axis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1608156

By:

Ma, Jingxin;
Lin, Sailing;
Zeng, Chuimian;
Wu, Wenhao;
Zhang, Qi;
Zhu, Guli;
Fang, Qiongfang;
Fan, Lijun;
Takeda, Shunichi;
Li, Xiaoyu;
Li, Xiushen;
Zhou, Yu;
Wu, Xueqing

Publication type:

Article

Interferon-γ causes myogenic cell dysfunction and senescence in immune myopathies.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 8, p. 2883, doi. 10.1093/brain/awaf153

By:

Hou, Cyrielle;
Periou, Baptiste;
Gervais, Marianne;
Martin, Ludovic;
Berthier, Juliette;
Baba-Amer, Yasmine;
Souvannanorath, Sarah;
Lechapt-Zalcman, Emmanuele;
Malfatti, Edoardo;
Gherardi, Romain K;
Relaix, Fréderic;
Bencze, Maximilien;
Authier, François-Jérôme

Publication type:

Article

Calcium overload via PVT1 reprograms neutrophil fate and constrains gastric cancer progression.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06912-6

By:

Wang, Dong;
Li, Yunlong;
Peng, Xiaoyu;
Zhang, Lulu;
Zhang, Ying;
Guan, Xue;
Liang, Xiao;
Fu, Songbin;
Yu, Jingcui

Publication type:

Article

Modulating senescence-associated secretory phenotype–driven paracrine effects to overcome therapy -induced senescence: senolytic effects of hesperidin and quercetin in A549 lung adenocarcinoma cells.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10904-6

By:

Iswarya, B R;
John, Cordelia Mano

Publication type:

Article

Regetting-18 complex powder (R-18CP) - A formulation of components from food-medicine and its anti-aging effects.

Published in:

Functional Foods in Health & Disease, 2025, v. 15, n. 7, p. 369, doi. 10.31989/ffhd.v15i7.1647

By:

YUAN, Lan;
DAVIS, Paul F.

Publication type:

Article

Oxidative stress, senescence and mRNA decay in peripheral blood mononuclear cells of women with gestational diabetes mellitus‐link to increased cardiovascular disease risk.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 9, p. 4802, doi. 10.1111/dom.16521

By:

Lekva, Tove;
Roland, Marie Cecilie Paasche;
Qvigstad, Elisabeth;
Khan, Yusuf;
Godang, Kristin;
Michelsen, Annika E.;
Ueland, Thor

Publication type:

Article

Fibro-NPC: a pathogenic subtype identified at single-cell resolution with secreted SFRP4 as a biomarker in intervertebral disc degeneration.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06798-4

By:

Xu, Yili;
Xie, Zuozhi;
Gu, Shubo;
Zhao, Xiang;
Zhao, Di;
Wu, Zhengzheng;
Wang, Jinfeng;
Xu, Tao;
Xu, Ruxue;
Feng, Zhenhua;
Qiu, Yong;
Zhu, Zezhang;
Yu, Yang;
Shi, Bo;
Jiang, Jun

Publication type:

Article

线粒体通过介导骨髓间充质干细胞影响骨代谢的机制.

Published in:

Chinese Journal of Osteoporosis, 2025, v. 31, n. 7, p. 1069, doi. 10.3969/j.issn.1006-7108.2025.07.023

By:

刘小峰;
储旭东;
刘亚兰;
张亚峰;
马勇;
郭杨;
尹恒;
李刚

Publication type:

Article

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease.

Published in:

Science Translational Medicine, 2025, v. 17, n. 810, p. 1, doi. 10.1126/scitranslmed.adv4071

By:

Arai, Yohei;
Chavkin, Nicholas W.;
Arai, Yuka;
Halvardson, Jonatan;
Bjurling, Josefin;
Doviak, Heather;
Cochran, Jesse D.;
Evans, Megan A.;
Horitani, Keita;
Yura, Yoshimitsu;
Miura-Yura, Emiri;
Sano, Soichi;
Forsberg, Lars A.;
Walsh, Kenneth

Publication type:

Article

Association of 25(OH)D serum level with biological aging: A Cross-Sectional Study of 2007–2016 NHANES surveys.

Published in:

PLoS ONE, 2025, v. 20, n. 8, p. 1, doi. 10.1371/journal.pone.0328107

By:

Feng, Yi;
Yu, Licheng;
Wang, Jue

Publication type:

Article

Biological aging and incident cardiovascular diseases in individuals with diabetes: insights from a large prospective cohort study.

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02855-w

By:

Zeng, Zhiwei;
Yu, Chunyu;
Chen, Runze;
Li, Zhongchen;
Wang, Peng;
Wang, Xueying;
Li, Xi;
Zheng, Zhe

Publication type:

Article

Menopausal status, transition, and age at menopause with accelerated biological aging across multiple organ systems: findings from two cohort studies.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04223-7

By:

Xiang, Yi;
Meng, Qiong;
Huang, Zitong;
Zhang, Ning;
Zhang, Yuan;
Ding, Xianbin;
Yu, Jianhong;
Baimakangzhuo;
Liu, Leilei;
Xiao, Xiong;
Zhao, Xing

Publication type:

Article

Enhancement of angiotensin II type 1 receptor-associated protein suppresses kidney inflammation in a mouse model of aristolochic acid nephropathy.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08642-7

By:

Furuta, Rika;
Urate, Shingo;
Wakui, Hiromichi;
Uehara, Tatsuki;
Tsukamoto, Shunichiro;
Taguchi, Shinya;
Morita, Ryutaro;
Okami, Naohito;
Yamashita, Akio;
Azushima, Kengo;
Tamura, Kouichi

Publication type:

Article

Single-cell transcriptome sequencing reveals the sphingolipid metabolism pathway plays an important role in leaf senescence in tobacco.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-07051-2

By:

Sun, Quan;
Hou, Bing;
Liu, Xinghui;
Zhang, Langlang;
Chang, Pingan;
Pang, Huimin;
He, Xiaohong;
Huang, Zexiang;
Zhang, Jili;
Liu, Guoxia;
Gong, Daping;
Chen, Mingli

Publication type:

Article

Endo180 and basement membrane stiffness induce OXPHOS and neoplastic transformation in aging prostate epithelia.

Published in:

NPJ Aging, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41514-025-00259-4

By:

Pastro, Lucia;
Martínez, Jennyfer;
Fontenla, Santiago;
Chiale, Ana C.;
Faulord, Agustina;
Frade, María P.;
Díaz, Andrea S.;
Martino-Kunsch, Rodrigo;
Castro, Laura;
Schenk, Lysann;
Quijano, Celia;
Sturge, Justin;
Rodríguez-Teja, Mercedes

Publication type:

Article

The 3D theory of osseointegration: material, topography, and time as interdependent determinants of bone–implant integration.

Published in:

International Journal of Implant Dentistry, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s40729-025-00639-1

By:

Ogawa, Takahiro;
Hirota, Makoto;
Shibata, Rune;
Matsuura, Takanori;
Komatsu, Keiji;
Saruta, Juri;
Att, Wael

Publication type:

Article

Association of epigenetic aging with plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in Hispanic/Latino adults.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01941-w

By:

Fornage, Myriam;
Tarraf, Wassim;
Daviglus, Martha L.;
DeCarli, Charles;
Gonzalez, Kevin A.;
Isasi, Carmen R.;
Kuwayama, Sayaka;
Lamar, Melissa;
Levin, Bonnie E.;
Parada Jr., Humberto;
Ramos, Alberto R.;
Rundek, Tatjana;
Thyagarajan, Bharat;
González, Hector M.

Publication type:

Article

Hallmarks and mechanisms of cellular senescence in aging and disease.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02655-x

By:

Ajoolabady, Amir;
Pratico, Domenico;
Bahijri, Suhad;
Eldakhakhny, Basmah;
Tuomilehto, Jaakko;
Wu, Feng;
Ren, Jun

Publication type:

Article

Exploring DNA methylation age and the influence of physical performance, and hypertension on frailty in elderly women.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13175-0

By:

Chitta, Pitaksin;
Barrow, Timothy M.;
Pratumvinit, Busadee;
Dawangpa, Atchara;
Kaewboonruang, Witchayaporn;
Khamrangsee, Saliltip;
Korolchuk, Viktor I.;
Sae-Lee, Chanachai

Publication type:

Article

Mechanisms of cell senescence and apoptosis in cyclophosphamide-induced premature ovarian failure in rats.

Published in:

Journal of Ovarian Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13048-025-01759-3

By:

Wu, Jiaqi;
Wei, Yanmeng;
Peng, Qiangli;
Zhu, Jing;
Shi, Huacong;
Zhao, Ting;
Yuan, Tao

Publication type:

Article

Association between coffee intake and serum α-Klotho levels in adults: a population-based study.

Published in:

BMC Public Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12889-025-23812-y

By:

Tang, Xiaoyan;
Tuo, Hu;
Cao, Cui;
Yang, Zhao;
Zhang, Shaohua;
Du, Rui

Publication type:

Article

P16-positive senescent cells promote DKD by the dysregulation of glycolysis and mitochondrial metabolism.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02650-2

By:

Lu, Xiao;
Wu, Jiao;
Agborbesong, Ewud;
Li, Xiaogang

Publication type:

Article

Enhancement of angiotensin II type 1 receptor-associated protein suppresses kidney inflammation in a mouse model of aristolochic acid nephropathy.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08642-7

By:

Furuta, Rika;
Urate, Shingo;
Wakui, Hiromichi;
Uehara, Tatsuki;
Tsukamoto, Shunichiro;
Taguchi, Shinya;
Morita, Ryutaro;
Okami, Naohito;
Yamashita, Akio;
Azushima, Kengo;
Tamura, Kouichi

Publication type:

Article

Elevated Senescence Markers in Developing Trisomy 21 Human Lungs.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 73, n. 2, p. 251, doi. 10.1165/rcmb.2024-0361OC

By:

Belgacemi, Randa;
Cherry, Caroline;
Thompson, Michael;
Koloko Ngassie, Maunick;
Rehan, Anika;
El Alam, Imad;
Jourdan Le Saux, Claude;
Glass, Ian;
Britt Jr., Rodney D.;
Prakash, Y. S.;
Pabelick, Christina;
Danopoulos, Soula;
Al Alam, Denise

Publication type:

Article

Chronic Obstructive Pulmonary Disease Airway Epithelial Cell–derived Extracellular Vesicles Spread Cellular Senescence via MicroRNA-34a.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 73, n. 2, p. 210, doi. 10.1165/rcmb.2024-0183OC

By:

Devulder, Justine V.;
Baker, Jonathan R.;
Fenwick, Peter S.;
Odqvist, Lina;
Donnelly, Louise E.;
Barnes, Peter J.

Publication type:

Article

Cancer-associated fibroblasts: dual roles from senescence sentinels to death regulators and new dimensions in therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1635771

By:

Ruan, Guixiang;
Wang, Xiang;
Ou, Huiyi;
Guo, Duancheng

Publication type:

Article

Identification of Biomarkers for Acute Myocardial Infarction Based on Cell Senescence Genes and Machine Learning.

Published in:

Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi, 2025, v. 29, n. 8, p. 409, doi. 10.14744/AnatolJCardiol.2025.5129

By:

Liya Li;
Pei Qin

Publication type:

Article

Exacerbated Cellular Senescence in Human Dopaminergic Neurons along with an Increase in LRRK2 Kinase Activity.

Published in:

Biocell, 2025, v. 49, n. 7, p. 1225, doi. 10.32604/biocell.2025.065486

By:

Ho, Dong Hwan;
Lee, Minhyung;
Nam, Daleum;
Kim, Hyejung;
Kim, Janghwan;
Seo, Mi Kyoung;
Park, Sung Woo;
Son, Ilhong

Publication type:

Article

The Role of Seaweed Derived Bioactive Compounds in Preventing Cellular Senescence and Aging.

Published in:

Natural Product Communications, 2025, v. 20, n. 6, p. 1, doi. 10.1177/1934578X251350769

By:

Kumarasinghe, Hiruni S;
Gunathilaka, Thilina L

Publication type:

Article

Radial Extracorporeal Shockwave Therapy Reduces Subchondral Osteoblast Senescence in Knee Osteoarthritis.

Published in:

American Journal of Sports Medicine, 2025, v. 53, n. 10, p. 2352, doi. 10.1177/03635465251355245

By:

Chen, Lin;
Zhang, Zhan;
Ma, Xun;
Zhang, Di;
Xu, Qi;
Wang, Qian;
Pan, Shinong;
He, Yu;
Liu, Xueyong

Publication type:

Article

Loss of p21 does not protect against premature ovarian insufficiency caused by alkylating agents.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1616965

By:

Lu, Xiaohui;
Han, Yongli;
Song, Jiaming;
Wan, Qin;
Liu, Pengfei;
Chen, Li;
Wang, Yufeng;
Xue, Pingping;
Dai, Xiuliang

Publication type:

Article

Oblici akumulacije lipofuscina u ganglijskim ćelijama gornjeg vratnog gangliona kod čoveka.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2008, v. 65, n. 10, p. 738

By:

Živkovič, Vladimir;
Stefanovič, Natalija;
Đurovič-Filipovič, Tatjana;
Pavlovič, Snežana;
Stojanovič, Vesna;
Bakič, Mirjana;
Kundalič, Braca;
Pavlovič, Miljana

Publication type:

Article

Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2020, v. 17, n. 4, p. 444, doi. 10.1080/15412555.2020.1797657

By:

Gu, Chao;
Zhang, Qi;
Ni, Dan;
Xiao, Qin-Feng;
Cao, Lin-Feng;
Fei, Chun-Yuan;
Ying, Ying;
Li, Na;
Tao, Feng

Publication type:

Article

Mammalian Target of Rapamycin: Is It Relevant to COPD Pathogenesis or Treatment?

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2019, v. 16, n. 1, p. 89, doi. 10.1080/15412555.2019.1583726

By:

Pasini, Evasio;
Flati, Vincenzo;
Comini, Laura;
Olivares, Adriana;
Bertella, Enrica;
Corsetti, Giovanni;
Vitacca, Michele

Publication type:

Article

The hydra of anesthetic neurotoxicity: Myth or reality?

Published in:

2018

By:

Graham, Marjory Ruth

Publication type:

Editorial

Synephrine Inhibits Oxidative Stress and H2O2-Induced Premature Senescence.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2607, doi. 10.1007/s12013-025-01669-7

By:

Abe, Hiroshi;
Indo, Hiroko P.;
Ito, Hiromu;
Majima, Hideyuki J.;
Tanaka, Tatsuro

Publication type:

Article

Hyperuricemia Facilitates Uric Acid-Mediated Vascular Endothelial Cell Damage by Inhibiting Mitophagy.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 1, p. 811, doi. 10.1007/s12013-024-01512-5

By:

Wu, Gang;
Liu, Jun;
Ma, Guirong;
Wei, Qiuyu;
Song, Xinghui

Publication type:

Article

Astragalus Polysaccharides Reduce High-glucose-induced Rat Aortic Endothelial Cell Senescence and Inflammasome Activation by Modulating the Mitochondrial Na+/Ca2+ Exchanger.

Published in:

Cell Biochemistry & Biophysics, 2022, v. 80, n. 2, p. 341, doi. 10.1007/s12013-021-01058-w

By:

Miao, Xin-Yu;
Zhu, Xiao-Xiao;
Gu, Zhao-Yan;
Fu, Bo;
Cui, Shao-Yuan;
Zu, Yuan;
Rong, Ling-Jun;
Hu, Fan;
Chen, Xiang-Mei;
Gong, Yan-Ping;
Li, Chun-Lin

Publication type:

Article

Functional Regulatory Mechanisms Underlying Bone Marrow Mesenchymal Stem Cell Senescence During Cell Passages.

Published in:

Cell Biochemistry & Biophysics, 2021, v. 79, n. 2, p. 321, doi. 10.1007/s12013-021-00969-y

By:

Iwata, T.;
Mizuno, N.;
Ishida, S.;
Kajiya, M.;
Nagahara, T.;
Kaneda-Ikeda, E.;
Yoshioka, M.;
Munenaga, S.;
Ouhara, K.;
Fujita, T.;
Kawaguchi, H.;
Kurihara, H.

Publication type:

Article

Identification of Differentially Expressed miRNAs in the Response of Spleen CD4+ T Cells to Electroacupuncture in Senescence-Accelerated Mice.

Published in:

Cell Biochemistry & Biophysics, 2020, v. 78, n. 1, p. 89, doi. 10.1007/s12013-020-00900-x

By:

Liu, Jianmin;
Liu, Jing;
Xiao, Ling;
Wang, Yawen;
Liu, Guangya;
Li, Jia;
Liang, Fengxia

Publication type:

Article