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Title
Influenza-induced production of interferon-alpha is defective in geriatric individuals.
Authors
Canaday, David H; Amponsah, Naa Ayele; Jones, Leola; Tisch, Daniel J; Hornick, Thomas R; Ramachandra, Lakshmi
Abstract
The majority of deaths (90%) attributed to influenza are in person's age 65 or older. Little is known about whether defects in innate immune responses in geriatric individuals contribute to their susceptibility to influenza.
Publication
Journal of clinical immunology, 2010, Vol 30, Issue 3, p373