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- Title
Preparation and characterization of 3D porous ceramic scaffolds based on portland cement for bone tissue engineering.
- Authors
Mansur, Alexandra A P; Mansur, Herman S
- Abstract
There is a constant need for bone substitutes. This work was focused on developing a porous substrate based on Portland cement with air-voids introduced by outgassing reaction product from lime and aluminum powder. The structures were obtained through two routes of raw-materials and processing. Water absorption and compressive strength measurements and scanning electron microscopy, X-ray diffraction, and Fourier Transformed Infrared Spectroscopy assays were conducted in order to characterize the porous substrates. The substrates have shown pore size structure compatible with bone tissue colonization. Also, the mechanical strength exhibited by the scaffolds fall in the normal ranges for trabecular bone. These characteristics indicate potential use of the developed porous scaffold for bone tissue engineering which was endorsed by in vitro experiments via cell culture.
- Publication
Journal of materials science. Materials in medicine, 2009, Vol 20, Issue 2, p497
- ISSN
0957-4530
- Publication type
Journal Article
- DOI
10.1007/s10856-008-3612-1