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- Title
Characterization of 3-hydroxyisobutyrate dehydrogenase, HIBADH, as a sperm-motility marker.
- Authors
Tasi, Yung-Chieh; Chao, Hsin-Chih Albert; Chung, Chia-Ling; Liu, Xiu-Ying; Lin, Ying-Ming; Liao, Pao-Chi; Pan, Hsien-An; Chiang, Han-Sun; Kuo, Pao-Lin; Lin, Ying-Hung
- Abstract
Asthenozoospermia is a major cause of male infertility. However, the molecular mechanisms underlying sperm-motility defects remain largely unknown in the majority of cases. In our previous study, we applied a proteomic approach to identify unknown proteins that were downregulated in spermatozoa with low motility compared to spermatozoa with good motility. Several sperm motility- related proteins have been identified. In this study, 3-hydroxyisobutyrate dehydrogenase (HIBADH), one of the proteins identified using the proteomic tools, is further characterized.
- Publication
Journal of assisted reproduction and genetics, 2013, Vol 30, Issue 4, p505
- ISSN
1573-7330
- Publication type
Journal Article
- DOI
10.1007/s10815-013-9954-8