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- Title
A prospective case series of high-risk infants who developed autism.
- Authors
Bryson, Susan E; Zwaigenbaum, Lonnie; Brian, Jessica; Roberts, Wendy; Szatmari, Peter; Rombough, Vicki; McDermott, Catherine
- Abstract
The present paper documents the development of autism/autistic spectrum disorder in a consecutive series of nine high-risk infants followed prospectively from 6 months of age. Evidence is provided for two broadly defined subgroups: the first subgroup (n = 6) showed a decrease in IQ between 12 and 24 or 36 months (from average/near average to severe cognitive impairment), whereas the second subgroup (n = 3) continued to obtain average or near average IQs. Signs of autism emerged and/or were more striking earlier in the first subgroup. In all nine children, early impairment in social-communicative development coexisted with atypical sensory and/or motor behaviors, as did a temperamental profile marked by irritability/distress and dysregulated state. Discussion focuses on issues raised by the pattern of findings.
- Publication
Journal of autism and developmental disorders, 2007, Vol 37, Issue 1, p12
- ISSN
0162-3257
- Publication type
Journal Article
- DOI
10.1007/s10803-006-0328-2