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- Title
Thymoma associated with malignancies may herald a hereditary cancer syndrome.
- Authors
Tehrani, Omid Saeed; Chen, Emily Q; Schaebler, David L; Mughal, Abdul W
- Abstract
Two probands with thymoma and other primary malignancies with multiple cancer patients in the family are described. Types of malignancies, pattern of pedigree and age of the patients do not match the known familial cancer syndromes. One proband was a very rare case with five discrete primary malignancies; TP53 sequencing and karyotyping did not reveal any mutations. These cases suggest thymoma associated malignancies may herald a hereditary cancer syndrome.
- Publication
Familial cancer, 2010, Vol 9, Issue 4, p655
- ISSN
1573-7292
- Publication type
Journal Article
- DOI
10.1007/s10689-010-9376-z