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- Title
A phase I evaluation of the combination of vinflunine and erlotinib in patients with refractory solid tumors.
- Authors
Sanoff, Hanna K; Davies, Janine M; Walko, Christine; Irvin, William; Buie, Larry; Keller, Kimberly; Ivanova, Anastasia; Chiu, Wing-Keung; O'Neil, Bert H; Stinchcombe, Thomas E; Dees, E Claire
- Abstract
Epidermal growth factor receptor (EGFR) inhibition may overcome chemotherapy resistance by inhibiting important anti-apoptotic signals that are constitutively activated by an overstimulated EGFR pathway.
- Publication
Investigational new drugs, 2011, Vol 29, Issue 5, p978
- ISSN
1573-0646
- Publication type
Journal Article
- DOI
10.1007/s10637-010-9427-1