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- Title
Abnormal breath testing in IBS: a meta-analysis.
- Authors
Shah, Eric D; Basseri, Robert J; Chong, Kelly; Pimentel, Mark
- Abstract
Recent evidence suggests a role for enteric bacteria in the development of symptoms in subjects with irritable bowel syndrome (IBS). The concept was initially based on the common finding of an abnormal lactulose breath test to suggest the presence of small intestinal bacterial overgrowth (SIBO). Despite successful antibiotic studies based on these findings, the premise of bacterial overgrowth was met with skepticism due to the perceived inaccuracies of breath testing in humans. In this study, we conduct a systematic review and meta-analysis of the studies using breath testing in IBS subjects with comparison to healthy controls.
- Publication
Digestive diseases and sciences, 2010, Vol 55, Issue 9, p2441
- ISSN
1573-2568
- Publication type
Journal Article
- DOI
10.1007/s10620-010-1276-4