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- Title
Associations of circulating retinol, vitamin E, and 1,25-dihydroxyvitamin D with prostate cancer diagnosis, stage, and grade.
- Authors
Gilbert, Rebecca; Metcalfe, Chris; Fraser, William D; Donovan, Jenny; Hamdy, Freddie; Neal, David E; Lane, J Athene; Martin, Richard M
- Abstract
Some epidemiological studies suggest that vitamin A (retinol), vitamin E, and vitamin D (total 25-hydroxyvitamin D, 25(OH)D; 1,25-dihydroxyvitamin, 1,25(OH)(2)D) are protective against prostate cancer. However, the evidence is not conclusive, with positive and null associations reported for all three vitamins. Limitations of previous studies include small sample size, lack of population controls, and reliance on self-reported dietary intake. Few studies have explored the interactions of circulating 25(OH)D with 1,25(OH)(2)D or retinol, which are biologically plausible interactions.
- Publication
Cancer causes & control : CCC, 2012, Vol 23, Issue 11, p1865
- ISSN
1573-7225
- Publication type
Journal Article
- DOI
10.1007/s10552-012-0052-5