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- Title
New cutpoints to identify increased HER2 copy number: analysis of a large, population-based cohort with long-term follow-up.
- Authors
Jensen, K C; Turbin, D A; Leung, S; Miller, M A; Johnson, K; Norris, B; Hastie, T; McKinney, S; Nielsen, T O; Huntsman, D G; Gilks, C B; West, R B
- Abstract
HER2 gene amplification and/or protein overexpression in breast cancer is associated with a poor prognosis and predicts response to anti-HER2 therapy. We examine the natural history of breast cancers in relationship to increased HER2 copy numbers in a large population-based study.
- Publication
Breast cancer research and treatment, 2008, Vol 112, Issue 3, p453
- ISSN
1573-7217
- Publication type
Journal Article
- DOI
10.1007/s10549-007-9887-y