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- Title
Paget's disease of the breast: the experience of the European Institute of Oncology and review of the literature.
- Authors
Caliskan, Mujgan; Gatti, Giovanna; Sosnovskikh, Irina; Rotmensz, Nicole; Botteri, Edoardo; Musmeci, Simona; Rosali dos Santos, Gabriela; Viale, Giuseppe; Luini, Alberto
- Abstract
Paget's disease of the breast is an uncommon presentation of breast malignancy, accounting for 1-3% of all the breast tumors and presents in different histopathologic patterns: in association with an underlying invasive or non invasive carcinoma, or without any underlying neoplasia. In the literature, different methods are used for the treatment. Mastectomy with or without axillary dissection has been considered as the standard treatment procedure for many years. Several studies have already shown that breast conservation with radiation therapy is an oncologically safe option. Regarding the axillary approach, several studies have documented the presence of positive sentinel lymph node even in Paget's disease alone. The objective of this study was to retrospectively analyze outcome of patients affected by Paget's breast disease and to define our institutional experience.
- Publication
Breast cancer research and treatment, 2008, Vol 112, Issue 3, p513
- ISSN
1573-7217
- Publication type
Journal Article
- DOI
10.1007/s10549-007-9880-5