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- Title
A phase II trial of Afimoxifene (4-hydroxytamoxifen gel) for cyclical mastalgia in premenopausal women.
- Authors
Mansel, Robert; Goyal, Amit; Nestour, Elisabeth Le; Masini-Etévé, Valérie; O'Connell, Katharine; Afimoxifene (4-OHT) Breast Pain Research Group
- Abstract
Many women experience symptoms of cyclical mastalgia, such as breast pain, tenderness, and nodularity. Tamoxifen and other drugs have been used to alleviate cyclical mastalgia symptoms; however, their use is associated with potentially serious side effects. The current study compared the safety and efficacy of two doses of a topical gel containing 4-hydroxytamoxifen (Afimoxifene, formerly known as 4-OHT) with placebo gel for the treatment of moderate to severe cyclical mastalgia.
- Publication
Breast cancer research and treatment, 2007, Vol 106, Issue 3, p389
- ISSN
0167-6806
- Publication type
Journal Article
- DOI
10.1007/s10549-007-9507-x