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- Title
Comparison of HER2 status between primary tumor and disseminated tumor cells in primary breast cancer patients.
- Authors
Solomayer, Erich F; Becker, Sven; Pergola-Becker, Graziella; Bachmann, Robert; Krämer, Bernhard; Vogel, Ulrich; Neubauer, Hans; Wallwiener, Diethelm; Huober, Jens; Fehm, Tanja N
- Abstract
The persistence of disseminated tumor cells (DTC) in bone marrow (BM) of breast cancer patients is associated with poor prognosis. Preliminary studies indicated that these patients might benefit from secondary adjuvant targeted therapy. HER2 protein is suggested as one of the most promising targets. The aims of this study were (1) to determine the HER2 status of DTC in BM of breast cancer patients and (2) to compare the HER2 status of DTC and corresponding primary tumors.
- Publication
Breast cancer research and treatment, 2006, Vol 98, Issue 2, p179
- ISSN
0167-6806
- Publication type
Journal Article
- DOI
10.1007/s10549-005-9147-y