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- Title
Decreased serum antioxidant capacity in patients with Wilson disease is associated with neurological symptoms.
- Authors
Bruha, Radan; Vitek, Libor; Marecek, Zdenek; Pospisilova, Lenka; Nevsimalova, Sona; Martasek, Pavel; Petrtyl, Jaromir; Urbanek, Petr; Jiraskova, Alena; Malikova, Ivana; Haluzik, Martin; Ferenci, Peter
- Abstract
Wilson disease (WD) is an inherited disorder of copper disposition caused by an ATP7B transporter gene mutation, leading to copper accumulation in predisposed tissues. In addition to a genetic predisposition, other factors are likely to contribute to its clinical manifestation. The aim of the study was to assess whether oxidative stress affects the phenotypic manifestation of WD.
- Publication
Journal of inherited metabolic disease, 2012, Vol 35, Issue 3, p541
- ISSN
1573-2665
- Publication type
Journal Article
- DOI
10.1007/s10545-011-9422-5