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- Title
Deletion of methylglyoxal synthase gene (mgsA) increased sugar co-metabolism in ethanol-producing Escherichia coli.
- Authors
Yomano, L P; York, S W; Shanmugam, K T; Ingram, L O
- Abstract
The use of lignocellulose as a source of sugars for bioproducts requires the development of biocatalysts that maximize product yields by fermenting mixtures of hexose and pentose sugars to completion. In this study, we implicate mgsA encoding methylglyoxal synthase (and methylglyoxal) in the modulation of sugar metabolism. Deletion of this gene (strain LY168) resulted in the co-metabolism of glucose and xylose, and accelerated the metabolism of a 5-sugar mixture (mannose, glucose, arabinose, xylose and galactose) to ethanol.
- Publication
Biotechnology letters, 2009, Vol 31, Issue 9, p1389
- ISSN
1573-6776
- Publication type
Journal Article
- DOI
10.1007/s10529-009-0011-8