We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Neuroprotective effect of potassium comenate against glutamate toxicity on the model of cultured rat cerebellar neurons.
- Authors
Shurygina, L V; Kravtsov, A A; Zlishcheva, E I; Nemchinova, E A; Bukin, D Yu
- Abstract
The study demonstrated neuroprotective action of novel chemical agent, potassium salt of comenic acid, against the glutamate-induced cytotoxicity on the model of cultured cerebral neurons. Potassium comenate (0.001-1.0 mM) significantly decreased the rate of glutamateinduced neuronal death. The highest viability of the cultured neurons during postglutamate time was observed when potassium comenate was applied in a concentration of 0.1 mM.
- Publication
Bulletin of experimental biology and medicine, 2014, Vol 158, Issue 1, p49
- ISSN
1573-8221
- Publication type
Journal Article
- DOI
10.1007/s10517-014-2689-4