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- Title
Role of prostatic epithelium basement membrane incompetence in the pathogenesis of chronic prostatitis.
- Authors
Stovbun, S V; Gomberg, M A; Bragina, E E; Sergienko, V E
- Abstract
Prostatic inflammation is associated with infections penetrating through the urethra. This inflammation is treated by long courses of wide-spectrum antibiotics. However, the most frequent cause of prostatitis is Escherichia coli and other enteric flora. Electron microscopy of biopsy specimens from the prostate detected gaps in the prostatic epithelium basement membrane, their size explaining the penetration of enteric flora into the prostate. These data suggest another view on the pathogenesis of prostatitis and approaches to improvement of therapy for this disease.
- Publication
Bulletin of experimental biology and medicine, 2012, Vol 152, Issue 4, p494
- ISSN
1573-8221
- Publication type
Journal Article
- DOI
10.1007/s10517-012-1561-7