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- Title
Inhibition of hemangioma development in a syngeneic mouse model correlates with bcl-2 suppression and the inhibition of Akt kinase activity.
- Authors
Mabeta, Peace; Pepper, Michael S
- Abstract
Hemangiomas are benign vascular tumors that are characterised by excessive angiogenesis. While there is no definitive treatment for these tumors, several angiogenesis inhibitors, including bleomycin, have been employed. To better understand the mechanism of bleomycin in accelerating haemangioma regression, we investigated the effects of the drug on hemangiomagenesis using a previously described mouse hemangioma model.
- Publication
Angiogenesis, 2012, Vol 15, Issue 1, p131
- ISSN
1573-7209
- Publication type
Journal Article
- DOI
10.1007/s10456-011-9248-7