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- Title
Urinary dysfunction and autonomic control in amyloid neuropathy.
- Authors
Ito, Takashi; Sakakibara, Ryuji; Yamamoto, Tatsuya; Uchiyama, Tomoyuki; Liu, Zhi; Asahina, Masato; Higashi, Morihiro; Arai, Kimihito; Ito, Shoichi; Awa, Yusuke; Yamamoto, Kaori; Kinou, Mika; Yamanishi, Tomonori; Hattori, Takamichi
- Abstract
Uro-neurological assessment was performed in four patients with small-fiber neuropathy due to amyloidosis (2 transthyretin-type/2 immunoglobulin light-chain-type). Voiding difficulties were due to detrusor weakness and impaired bladder sensation. In two patients cholinesterase inhibition treatment caused urge incontinence, indicating detrusor denervation supersensitivity. The underlying mechanisms of urinary dysfunction seem to involve postganglionic cholinergic and afferent somatic nerves.
- Publication
Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2006, Vol 16, Issue 1, p66
- ISSN
0959-9851
- Publication type
Journal Article
- DOI
10.1007/s10286-006-0319-6