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- Title
Gynecomastia associated with low-dose methotrexate therapy for rheumatoid arthritis.
- Authors
Abe, Koki; Mitsuka, Takeshi; Kanamori, Shigeo; Yamashita, Keishi; Yamaoka, Akiyoshi
- Abstract
A 68-year-old man with a 3-year history of rheumatoid arthritis (RA) developed gynecomastia 3 months after beginning oral low-dose methotrexate (MTX) therapy. Four months after MTX therapy was discontinued, the gynecomastia symptoms improved. Only eight cases of gynecomastia resulting from low-dose MTX administration have been reported worldwide, and no cases have previously been reported in Japan. Although it occurs infrequently, gynecomastia resulting from low-dose MTX therapy should be considered in male patients with RA.
- Publication
Modern rheumatology, 2007, Vol 17, Issue 6, p511
- ISSN
1439-7595
- Publication type
Journal Article
- DOI
10.1007/s10165-007-0619-2