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- Title
Value and level of circulating endothelial progenitor cells, angiogenesis factors and mononuclear cell apoptosis in patients with chronic kidney disease.
- Authors
Chen, Yen-Ta; Cheng, Ben-Chung; Ko, Sheung-Fat; Chen, Chih-Hung; Tsai, Tzu-Hsien; Leu, Steve; Chang, Hsueh-Wen; Chung, Sheng-Ying; Chua, Sarah; Yeh, Kuo-Ho; Chen, Yung-Lung; Yip, Hon-Kan
- Abstract
Chronic renal failure on dialysis can reduce the number of circulating endothelial progenitor cells (EPCs), but this biomarker has not been fully investigated in patients with chronic kidney disease (CKD). A link between CKD and increased mononuclear cell apoptosis (MCA) in circulation has been reported but the effect of vascular endothelial growth factor (VEGF) and stromal cell-derived factor (SDF)-1α, two angiogenesis factors, on circulating EPC levels in CKD has not been clarified. This study examined the relationships between the numbers of circulating EPCs and the severity of CKD, degree of MCA and serum levels of VEGF and SDF-1α in CKD patients.
- Publication
Clinical and experimental nephrology, 2013, Vol 17, Issue 1, p83
- ISSN
1437-7799
- Publication type
Journal Article
- DOI
10.1007/s10157-012-0664-9