We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Host cell targets of tegument protein VP22 of herpes simplex virus 1.
- Authors
Li, Meili; Wang, Lin; Ren, Xiaoming; Zheng, Chunfu
- Abstract
In the present study, seven novel host cell factors associated with VP22 were identified from the human leukocyte cDNA library using a yeast two-hybrid high-throughput screening system. To confirm some of the interactions, VP22 and its homologues and two candidate targets were tagged with enhanced cyan or yellow fluorescent protein. While RING finger protein 10 (RNF10), WD repeat-containing protein 42A (WDR42A) or VP22 alone showed distinct subcellular localization patterns, RNF10 and WDR42A were relocated when co-expressed with VP22 or its homologues. Thus, these potential host cell factors of VP22 might expand the list of the host targets of VP22.
- Publication
Archives of virology, 2011, Vol 156, Issue 6, p1079
- ISSN
1432-8798
- Publication type
Journal Article
- DOI
10.1007/s00705-011-0960-9