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- Title
Molecular phylogeny of modern coxsackievirus A16.
- Authors
Perera, D; Yusof, M A; Podin, Y; Ooi, M H; Thao, N T T; Wong, K K; Zaki, A; Chua, K B; Malik, Y A; Tu, P V; Tien, N T K; Puthavathana, P; McMinn, P C; Cardosa, M J
- Abstract
A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7-30.2% and 19.9-25.2% in VP1 and VP4, respectively, in relation to other CVA16 strains, which formed two separate lineages in genogroup B with nucleotide variation of less than 13.4% and less than 16.3% in VP1 and VP4, respectively. Lineage 1 strains circulating before 2000 were later displaced by lineage 2 strains.
- Publication
Archives of virology, 2007, Vol 152, Issue 6, p1201
- ISSN
0304-8608
- Publication type
Journal Article
- DOI
10.1007/s00705-006-0934-5