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- Title
Detection of two porcine circovirus type 2 genotypic groups in United States swine herds.
- Authors
Cheung, A K; Lager, K M; Kohutyuk, O I; Vincent, A L; Henry, S C; Baker, R B; Rowland, R R; Dunham, A G
- Abstract
In late 2005, sporadic cases of an acute onset disease of high mortality were observed in 10- to 16-week-old growing pigs among several swine herds of the United States. Tissues from the affected pigs in Kansas, Iowa, and North Carolina were examined, and porcine circovirus type 2 (PCV2) was detected consistently among these tissues. Phylogenetically, PCV2 can be divided into two major genotypic groups, PCV2-group 1 and PCV2-group 2. Whereas PCV2-group 1 isolates were detected in all the diseased animals, only two of the diseased animals harbored PCV2-group 2 isolates. This observation is important because PCV2-group 1 isolates had never been reported in the United States before (GenBank as of May 16, 2006), and they are closely related to the PCV2-group 1 isolates that have been described in Europe and Asia, previously. Our analysis revealed that each genotypic group contains a distinct stretch of nucleotide or amino acid sequence that may serve as a signature motif for PCV2-group 1 or PCV2-group 2 isolates.
- Publication
Archives of virology, 2007, Vol 152, Issue 5, p1035
- ISSN
0304-8608
- Publication type
Journal Article
- DOI
10.1007/s00705-006-0909-6