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- Title
Imaging of human brain tumor tissue by near-infrared laser coherence tomography.
- Authors
Böhringer, H J; Lankenau, E; Stellmacher, F; Reusche, E; Hüttmann, G; Giese, A
- Abstract
Intraoperative detection of residual tumor remains an important challenge in surgery to treat gliomas. New developments in optical techniques offer non-invasive high-resolution imaging that may integrate well into the workflow of neurosurgical operations. Using an intracranial glioma model, we have recently shown that time domain optical coherence tomography (OCT) allows discrimination of normal brain, diffusely invaded brain tissue, and solid tumor. OCT imaging allowed acquisition of 2D and 3D data arrays for multiplanar analysis of the tumor to brain interface. In this study we have analyzed biopsy specimens of human brain tumors and we present the first feasibility study of intraoperative OCT and post-image acquisition processing for non-invasive imaging of the brain and brain tumor.
- Publication
Acta neurochirurgica, 2009, Vol 151, Issue 5, p507
- ISSN
0942-0940
- Publication type
Journal Article
- DOI
10.1007/s00701-009-0248-y