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- Title
Dual proton pump inhibitor plus amoxicillin as an empiric anti-H. pylori therapy: studies from the United States.
- Authors
Graham, David Y; Javed, Syed Ussama; Keihanian, Sara; Abudayyeh, Suhaib; Opekun, Antone R
- Abstract
Studies with CYP2C19 slow metabolizers have shown that the combination of a proton pump inhibitor (PPI) plus amoxicillin (dual therapy) can reliably cure more than 90% of Helicobacter pylori infections. Theoretically, the use of a PPI dose that provides equivalent acid suppression with fast metabolizers and slow metabolizers would achieve high cure rates irrespective of the CYP2C19 genotype.
- Publication
Journal of gastroenterology, 2010, Vol 45, Issue 8, p816
- ISSN
1435-5922
- Publication type
Journal Article
- DOI
10.1007/s00535-010-0220-x