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- Title
The role of S-adenosylmethionine in preventing oxaliplatin-induced liver toxicity: a retrospective analysis in metastatic colorectal cancer patients treated with bevacizumab plus oxaliplatin-based regimen.
- Authors
Vincenzi, Bruno; Daniele, Santini; Frezza, Anna Maria; Berti, Pierpaolo; Vespasiani, Umberto; Picardi, Antonio; Tonini, Giuseppe
- Abstract
Hepatotoxicity represents a frequent chemotherapy-related side effect, often associated with course delays, discontinuations, and dose reductions. S-adenosylmethionine (AdoMet) administration is effective in the treatment of a variety of liver injuries, but it has never been evaluated in the prevention of chemotherapy-induced damage.
- Publication
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Vol 20, Issue 1, p135
- ISSN
1433-7339
- Publication type
Journal Article
- DOI
10.1007/s00520-010-1078-4