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- Title
Y chromosome haplotypes reveal prehistorical migrations to the Himalayas.
- Authors
Bing Su; ChunjieXiao; Ranjan Deka; Seielstad, Mark T.; Kangwanpong, Daoroong; Junhua Xiao; Daru Lu; Underhill, Peter; Cavalli-Sforza, Luca; Chakraborty, Ranajit; Li Jin
- Abstract
By using 19 Y chromosome biallelic markers and 3 Y chromosome microsatellite markers, we analyzed the genetic structure of 31 indigenous Sino-Tibetan speaking populations (607 individuals) currently residing in East, Southeast, and South Asia. Our results showed that a T to C mutation at locus M122 is highly prevalent in almost all of the Sino-Tibetan populations, implying a strong genetic affinity among populations in the same language family. Furthermore, the extremely high frequency of H8, a haplotype derived from M122C, in the Sino-Tibetan speaking populations in the Himalayas including Tibet and northeast India indicated a strong bottleneck effect that occurred during a westward and then southward migration of the founding population of Tibeto-Burmans. We, therefore, postulate that the ancient people, who lived in the upper-middle Yellow River basin about 10,000 years ago and developed one of the earliest Neolithic cultures in East Asia, were the ancestors of modern Sino-Tibetan populations.
- Publication
Human Genetics, 2000, Vol 107, Issue 6, p582
- ISSN
0340-6717
- Publication type
Academic Journal
- DOI
10.1007/s004390000406