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- Title
Sirolimus, a promising treatment for refractory Kaposiform hemangioendothelioma.
- Authors
Kai, Li; Wang, Zuopeng; Yao, Wei; Dong, Kuiran; Xiao, Xianmin
- Abstract
Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular tumor that usually occurs in infants. It is commonly associated with Kasabach-Merritt phenomenon which is directly responsible for the significant morbidity and mortality, including hemodynamic instability, local invasion, and compression of vital structures. Treatment is particularly difficult for those who had no response to conventional therapies. This paper wants to share experience of mTOR inhibitors sirolimus in the treatment of refractory KHE.
- Publication
Journal of cancer research and clinical oncology, 2014, Vol 140, Issue 3, p471
- ISSN
1432-1335
- Publication type
Journal Article
- DOI
10.1007/s00432-013-1549-3