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- Title
A genomewide survey of developmentally relevant genes in Ciona intestinalis. IV. Genes for HMG transcriptional regulators, bZip and GATA/Gli/Zic/Snail.
- Authors
Yamada, Lixy; Kobayashi, Kenji; Degnan, Bernard; Satoh, Nori; Satou, Yutaka
- Abstract
Many kinds of transcription factors and regulators play key roles in a variety of developmental processes. In the present survey, genes encoding proteins with conserved HMG-box, bZip domains, and some types of zinc finger motifs were surveyed in the completely sequenced genome of Ciona intestinalis. In the present analysis, 21 HMG-box-containing genes and 26 bZip genes were identified as well as four small groups of zinc finger genes in the Ciona genome. The results also showed that a less redundant set of genes is present in the Ciona genome compared with vertebrate genomes. In addition, cDNA clones for almost all genes identified have been cloned and distributed as a " Ciona intestinalis Gene Collection Release I". The present comprehensive analysis therefore provides a means to study the role of these transcription factors in developmental processes of basal chordates.
- Publication
Development genes and evolution, 2003, Vol 213, Issue 5-6, p245
- ISSN
0949-944X
- Publication type
Journal Article
- DOI
10.1007/s00427-003-0316-x