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- Title
Islet cell transplantation today.
- Authors
Bretzel, Reinhard G; Jahr, Henning; Eckhard, Michael; Martin, Isabel; Winter, Daniel; Brendel, Mathias D
- Abstract
Long-term studies strongly suggest that tight control of blood glucose can prevent the development and retard the progression of chronic complications of type 1 diabetes mellitus. In contrast to conventional insulin treatment, replacement of a patient's islets of Langerhans either by pancreas organ transplantation or by isolated islet transplantation is the only treatment to achieve a constant normoglycemic state and avoiding hypoglycemic episodes, a typical adverse event of multiple daily insulin injections. However, the cost of this benefit is still the need for immunosuppressive treatment of the recipient with all its potential risks.
- Publication
Langenbeck's archives of surgery, 2007, Vol 392, Issue 3, p239
- ISSN
1435-2443
- Publication type
Journal Article
- DOI
10.1007/s00423-007-0183-4