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- Title
Subconjunctival sirolimus in the treatment of diabetic macular edema.
- Authors
Krishnadev, Nupura; Forooghian, Farzin; Cukras, Catherine; Wong, Wai; Saligan, Leorey; Chew, Emily Y; Nussenblatt, Robert; Ferris, Frederick, 3rd; Meyerle, Catherine
- Abstract
Diabetic macular edema (DME) is a leading cause of blindness in the developed world. Sirolimus has been shown to inhibit the production, signaling, and activity of many growth factors relevant to the development of diabetic retinopathy. This phase I/II study assesses the safety of multiple subconjunctival sirolimus injections for the treatment of DME, with some limited efficacy data.
- Publication
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2011, Vol 249, Issue 11, p1627
- ISSN
1435-702X
- Publication type
Journal Article
- DOI
10.1007/s00417-011-1694-9