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- Title
Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation--a longitudinal follow-up study.
- Authors
Lemiere, Jurgen; Decruyenaere, Marleen; Evers-Kiebooms, Gery; Vandenbussche, Erik; Dom, Rene
- Abstract
Objective information about the onset and progression of cognitive impairment in Huntington's disease (HD) is very important in the light of appropriate outcome measures when conducting clinical trials. Therefore, we evaluated the progression of cognitive functions in HD patients and asymptomatic carriers of the HD mutation (AC) over a 2.5-year period. We also sought to detect the earliest markers of cognitive impairment in AC.
- Publication
Journal of neurology, 2004, Vol 251, Issue 8, p935
- ISSN
0340-5354
- Publication type
Journal Article
- DOI
10.1007/s00415-004-0461-9