We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Monoallelic gene expression in mammals.
- Authors
Zakharova, Irina S; Shevchenko, Alexander I; Zakian, Suren M
- Abstract
Three systems of monoallelic gene expression in mammals are known, namely, X-chromosome inactivation, imprinting, and allelic exclusion. In all three systems, monoallelic expression is regulated epigenetically and is frequently directed by long non-coding RNAs (ncRNAs). This review briefs all three systems of monoallelic gene expression in mammals focusing on chromatin modifications, spatial chromosome organization in the nucleus, and the functioning of ncRNAs.
- Publication
Chromosoma, 2009, Vol 118, Issue 3, p279
- ISSN
1432-0886
- Publication type
Journal Article
- DOI
10.1007/s00412-009-0206-8