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- Title
Treatment outcomes in elderly with advanced-stage non-small cell lung cancer.
- Authors
Tam, Terence Chi-Chun; Ho, James Chung-Man; Wong, Matthew King-Yan; Wong, Wai-Mui; Wang, Julie Kwan-Ling; Lam, Jamie Chung-Mei; Lui, Macy Mei-Sze; Lam, Wah-Kit; Ip, Mary Sau-Man; Lam, David Chi-Leung
- Abstract
Lung cancer remains the top cause of cancer morbidity and mortality in the world. Although the identification of epidermal growth factor receptor (EGFR) gene mutations could predict efficacy of tyrosine kinase inhibitor (TKI), testing for predictive biomarkers are not always possible due to tissue availability. The overall therapeutic decision remains a clinical one for a significant proportion of elderly patients with advanced stage lung cancer but no known EGFR mutation status. The purpose of this study was to compare the outcome of drug treatment modalities in progression-free survival (PFS) and overall survival (OS) for elderly with advanced-stage non-small cell lung cancer (NSCLC) and to identify clinical parameters that could predict treatment outcome.
- Publication
Lung, 2013, Vol 191, Issue 6, p645
- ISSN
1432-1750
- Publication type
Journal Article
- DOI
10.1007/s00408-013-9498-9