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Title
Serum cystatin C and emphysema: results from the National Health and Nutrition Examination Survey (NHANES).
Authors
Rokadia, Haala K; Agarwal, Shikhar
Abstract
Cystatin C (CysC) is a potent nonorgan-specific cysteine protease inhibitor and may contribute to elastolysis and tissue destruction by a mechanism of protease–antiprotease imbalance. Given the prevalence of CysC in the serum of smokers and its role in tissue destruction, we aimed to evaluate the association between CysC and emphysema.